Type: | Family | Name: | Transcription regulator, P21/BotR , Clostridium toxin-associated |
Description: | Regulatory sigma-70 protein, BotR transcription regulator regulates neurotoxin production in Clostridium botulinum. Similarly, tetanus toxin production of Clostridium tetaniis regulated by TetR which is a very close relative of BotR. Functional complementation experiments have been done for botR and tetR in highly transformable strain of Clostridium perfringenshost cells to assess functional interchangeability of sigma factors and it has been confirmed that they are interchangeable in vivo []. | Short Name: | Tscrpt_reg_p21/BotR |