Type: | Family | Name: | HTH-type transcriptional regulator RamB |
Description: | This protein family includes the HTH-type transcriptional regulator RamB (Rv0465c/MT0481). In Corynebacterium glutamicum RamB controls the expression of several genes involved in acetate metabolism []. In Mycobacterium tuberculosis RamB is involved in the control of the glyoxylate cycle [] and its paralogue PrpR in the regulation of the methylcitrate pathway []. Family members contain a helix-turn-helix (HTH) motif, which is a major structural motif capable of binding DNA. Many proteins with this motif have been shown to regulate gene expression. | Short Name: | HTH_RamB |