Protein Domain : IPR013795

Type:  Family Name:  DNA/RNA-binding protein Alba
Description:  The DNA/RNA-binding protein Alba binds double-stranded DNA tightly but without sequence specificity. It binds rRNA and mRNA in vivo, and may play a role in maintaining the structural and functionalstability of RNA, and, perhaps, ribosomes. It is distributed uniformly and abundantly on the chromosome. Alba has been shown to bind DNA and affect DNA supercoiling in a temperature dependent manner []. It is regulated by acetylation (alba = acetylation lowers binding affinity) by the Sir2 protein. Alba is proposed to play a role in establishment or maintenance of chromatin architecture and thereby in transcription repression. For further information see []. Short Name:  DNA/RNA-bd_Alba
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0 Child Features

0 Contains

3 Cross Referencess

Identifier
PIRSF028732
TIGR00285
MF_01122

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003677 IPR013795
GO:0003723 IPR013795
GO:0005737 IPR013795

3 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR013795
GO:0003723 IPR013795
GO:0005737 IPR013795

1 Parent Features

DB identifier Type Name
IPR002775 Family DNA/RNA-binding protein Alba-like

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10869069
            16256418