Type: | Family | Name: | Peptidase S54, rhomboid, metazoan |
Description: | This entry represents metazoan rhomboid proteins (), integral membrane proteins thought to be involved in regulated intra-membrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors []. Rhomboid proteins cleave type-1 transmembrane domains using a catalytic triad composed of serine, histidine and asparagine contributed by different transmembrane domains. These proteins belong to the S54 peptidase family of proteins. | Short Name: | Peptidase_S54_rhomboid_met |