Protein Domain : IPR027146

Type:  Family Name:  Neuropilin-1
Description:  Neuropilins are essential multifunctional vertebrate cell surface receptors []. They function as receptors for axon guidance factor semaphorin class 3 (Sema3), vascular endothelial growth factor (VEGF) and placenta growth factor-2 (PLGF-2).Neuropilin-1 is involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, the PLGF-2 isoform of PLGF, the VEGF-165 isoform of VEGF and VEGF-B [, , , ]. Short Name:  NRP1
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10127:SF616

0 Found In

9 GO Annotations

GO Term Gene Name
GO:0005021 IPR027146
GO:0017154 IPR027146
GO:0019838 IPR027146
GO:0001525 IPR027146
GO:0007411 IPR027146
GO:0009887 IPR027146
GO:0035767 IPR027146
GO:0048010 IPR027146
GO:0071526 IPR027146

9 Ontology Annotations

GO Term Gene Name
GO:0005021 IPR027146
GO:0017154 IPR027146
GO:0019838 IPR027146
GO:0001525 IPR027146
GO:0007411 IPR027146
GO:0009887 IPR027146
GO:0035767 IPR027146
GO:0048010 IPR027146
GO:0071526 IPR027146

1 Parent Features

DB identifier Type Name
IPR014648 Family Neuropilin

0 Proteins

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            23116416
            20133938
            9288753
            9529250
            10688880