Type: | Conserved_site | Name: | Protein phosphatase 2A regulatory subunit PR55, conserved site |
Description: | Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase implicated in many cellular processes, including the regulation of metabolic enzymes and proteins involved in signal transduction [, ]. PP2A is a trimercomposed of a 36 kDa catalytic subunit, a 65 kDa regulatory subunit (subunit A) and a variable third subunit (subunit B) [, ].One form of the third subunit is a 55 kDa protein (PR55), which exists in Drosophila melanogasterand yeast, and has up to three forms in mammals [, ]. PR55 may actas a substrate recognition unit, or may help to target the enzyme to the correct subcellular location [].This entry represents conserved regions found in the N-terminal region and the centre of these proteins. | Short Name: | PP2A_PR55_CS |