Protein Domain : IPR012006

Type:  Family Name:  tRNA nucleotidyltransferase, proteobacteria
Description:  This family predominantly consists of bacterial versions of tRNA adenylyltransferases. tRNA nuceotidyltransferases are responsible for the synthesis or repair of the 3' terminal CCA sequence of tRNA molecules. They are encoded by essential genes in almost all organisms and add the three ribonucleotides C, C, and A to the 3' end of tRNAs in sequential order. Most members of this family contain an additional metal dependent phosphohydrolase domain (HD). Although the precise functional role of this domain is undetermined, the demonstration in Escherichia coliof 2',3'-cyclic phosphodiesterase, 2'-nucleotidase, and phosphatase activities has led to the suggestion that it is involved in the repair of the CCA terminus [].For additional information please see [, , , , ]. Short Name:  CCA_bact
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0 Child Features

2 Contains

DB identifier Type Name
IPR003607 Domain HD/PDEase domain
IPR002646 Domain Poly A polymerase, head domain

3 Cross Referencess

Identifier
PIRSF000813
MF_01261
MF_01262

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0003723 IPR012006
GO:0004810 IPR012006
GO:0005524 IPR012006
GO:0001680 IPR012006

4 Ontology Annotations

GO Term Gene Name
GO:0003723 IPR012006
GO:0004810 IPR012006
GO:0005524 IPR012006
GO:0001680 IPR012006

0 Parent Features

0 Proteins

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10447505
            9868367
            10075991
            10943560
            12526808
            15210699