Protein Domain : IPR017985

Type:  Conserved_site Name:  DNA methylase, N-4 cytosine-specific, conserved site
Description:  Synonym(s): N-4 cytosine-specific DNA methylase, Modification methylase Site-specific DNA-methyltransferase (cytosine-N4-specific) () are enzymes that specifically methylate the amino group at the C-4 position of cytosines in DNA. In prokaryotes, the major role of DNA methylation is to protect host DNA against degradation by restriction enzymes. There are two major classes of DNA methyltransferase that differ in the nature of the modifications they effect. The members of one class (C-MTases) methylate a ring carbon and form C5-methylcytosine and members of the second class (N-MTases) methylate exocyclic nitrogens and form either N4-methylcytosine (N4-MTases) orN6-methyladenine (N6-MTases). Both classes of MTase utilise the cofactor S-adenosyl-L-methionine (SAM) as the methyl donor and are active as monomeric enzymes []. Short Name:  MeTrfase_CN4_CS
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0 Child Features

0 Contains

1 Cross References

Identifier
PS00093

2 Found Ins

DB identifier Type Name
IPR002941 Domain DNA methylase N-4/N-6
IPR001091 Family Restriction/modification DNA-methylase

3 GO Annotations

GO Term Gene Name
GO:0003677 IPR017985
GO:0015667 IPR017985
GO:0090124 IPR017985

3 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR017985
GO:0015667 IPR017985
GO:0090124 IPR017985

0 Parent Features

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7663118