Protein Domain : IPR031176

Type:  Family Name:  ELL/occludin family
Description:  This entry represents the ELL/occludin family. Occludin is found in the tight junction and may play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier []. ELL is a family of RNA polymerase II elongation factors. It is bound stably to elongation-associated factors 1 and 2, EAFs, and together these act as a strong regulator of transcription activity by direct interaction with Pol II. ELL binds to pol II on its own but the affinity is greatly increased by the cooperation of EAF []. Short Name:  ELL/occludin

6 Child Features

DB identifier Type Name
IPR002958 Family Occludin
IPR031184 Family RNA polymerase II elongation factor ELL
IPR031182 Family Occludin/ELL domain-containing protein 1
IPR031177 Family MARVEL domain-containing protein 2
IPR031175 Family RNA polymerase II elongation factor ELL3
IPR031179 Family RNA polymerase II elongation factor ELL2

0 Contains

1 Cross References

Identifier
PTHR23288

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17150956
            19114660