| Type: | Family | Name: | Probable pantothenate synthetase/4-phosphopantoate--beta-alanine ligase |
| Description: | Proteins in this family include pantothenate synthetase () from Methanosarcina mazei and 4-phosphopantoate--beta-alanine ligase () from Pyrococcus kodakaraensis. Pantothenate synthetase catalyses the condensation of pantoate with beta-alanine in an ATP-dependent and ADP-producing reaction []. 4-phosphopantoate--beta-alanine ligase catalyses the conversion of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway. It cannot use (R)-pantoate as substrate and thus does not display pantothenate synthetase (PS) activity []. | Short Name: | PPS |
