3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0007165 | IPR027138 |
| GO:0007250 | IPR027138 |
| GO:0046330 | IPR027138 |
| Type: | Family | Name: | TNF receptor-associated factor 4 |
| Description: | TNF receptor-associated factor 4 (TRAF4) is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. TRAF4 plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. It regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. TRAF4 modulates TRAF6 functions [, , , , , ]. In mouse, it has been shown to be required for normal skeleton development, and for normal development of the respiratory tract []. | Short Name: | TRAF4 |
| GO Term | Gene Name |
|---|---|
| GO:0007165 | IPR027138 |
| GO:0007250 | IPR027138 |
| GO:0046330 | IPR027138 |
