1 Child Features
| DB identifier | Type | Name |
|---|---|---|
| IPR013501 | Family | Ethanolamine utilization protein, PduT-related |
| Type: | Family | Name: | Polyhedral organelle shell protein PduT |
| Description: | Members of this group are polyhedral organelle shell proteins: pduT of Salmonella entericaand its orthologs in the propriondiol and ethanolamine operons of bacteria [, , ]. Some non-autotrophic organisms form polyhedral organelles, enterosomes [], that resemble the carboxysomes found in autotrophs, particularly the cyanobacteria. Carboxysomes are well-studied polyhedral organelles found in cyanobacteria and some chemoautotrophs [, ]. They are composed of a proteinaceous shell that houses most of the cell s ribulose bisphosphate carboxylase/oxygenase (RuBisCO). They are required for autotrophic growth at low CO2concentrations and are thought to function as part of a CO2-concentrating mechanism [, ].Polyhedral organelles, enterosomes, from non-autotrophic organisms are involved in coenzyme B12-dependent 1,2-propanediol utilization (e.g., in S. enterica, []) and ethanolamine utilization (e.g., in Salmonella typhimurium[]). Genes needed for enterosome formation are located in the 1,2-propanediol utilization pdu[, ] or ethanolamine utilization eut[, ] operons, respectively. Although enterosomes of non-autotrophic organisms are apparently related tocarboxysomes structurally, a functional relationship is uncertain. A role in CO2concentration, similar to that of the carboxysome, is unlikely since there is no known association between CO2and coenzyme B12-dependent 1,2-propanediol or ethanolamine utilization [].In S. enterica the propriondiol degrading enterosome consists of at least 15 proteins, of which, at least, seven are shell proteins: pduA [], pduB, B', J, K, T and U. In addition the organelle contains four enzymes: B12-dependent diol dehydratase (pduCDE) and its reactivating factor (pduGH), CoA-dependent proprionaldehyde dehydrogenase (pduP, []) and adenosyl transferase (pduO) [].It has been suggested that enterosomes sequester toxic aldehydes formed during both 1,2-propanediol and ethanolamine degradation and channel them to subsequent pathway enzymes. It has also been suggested that polyhedra might be used to protect diol dehydratase and ethanolamine ammonia-lyase from oxygen, to which both are sensitive [, ]. Mutational studies of PduA indicate that the organelles of S. enterica are not involved in concentrating 1,2-propanediol or CN-B12, but are consistent with a role in moderating aldehyde toxicity [, ].Other polyhedral organelle proteins are in (a closely related group), , , and . The latter two are very distantly related to this group and . Please see , , for more information on propanediol and ethanolamine utilization pathways and [, , ] for information on the pduand etuoperons. | Short Name: | Organelle_shell_prot_PduT |
| DB identifier | Type | Name |
|---|---|---|
| IPR013501 | Family | Ethanolamine utilization protein, PduT-related |
