Protein Domain : IPR027286

Type:  Family Name:  Prostacyclin synthase
Description:  Prostacyclin synthase (also known as prostaglandin I2 (prostacyclin) synthase (PTGIS) or CYP8A1) () catalyses the isomerization of prostaglandin H2 to prostacyclin. It plays an important role for prostanoid biosynthesis in humans. Although it shows homology with cytochrome P450, it does not require molecular oxygen. Instead it uses its heme cofactor to catalyse the isomerization of prostaglandin H2 to prostacyclin [, ]. Short Name:  PTGIS
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0 Child Features

0 Contains

1 Cross References

Identifier
PIRSF500628

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0008116 IPR027286
GO:0001516 IPR027286

2 Ontology Annotations

GO Term Gene Name
GO:0008116 IPR027286
GO:0001516 IPR027286

1 Parent Features

DB identifier Type Name
IPR024204 Family Cytochrome P450, cholesterol 7-alpha-monooxygenase-type

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            6338016
            11281454