Type: | Family | Name: | Helicase Sen1-like |
Description: | This entry includes helicase Sen1 and Sen1-lke proteins.The yeast helicase Sen1 is a subunit of the Nrd1 complex (Nrd1-Nab3-Sen1), which interacts with the exosome to mediate 3' end formation of some mRNAs, snRNAs and snoRNAs []. In Schizosaccharomyces pombe, Sen1 functions as an ATP-dependent 5'->3' DNA/RNA helicase required for the expression and maturation of diverse classes of non-protein-coding RNAs []. It may also play a role in transcription-coupled nucleotide excision repair []. MAGATAMA 3 is a Sen1-like protein that may regulate RNA molecules. In plants, it is involved in nucleolar organisation and pollen tube guidance [, ]. | Short Name: | Sen1-like |