Protein Domain : IPR012267

Type:  Family Name:  Peptidase S1A, acrosin
Description:  This group of proteins are serine peptidases belonging to MEROPS peptidase family S1, subfamily S1A (chymotrypsin, clan PA(S)). Members of this family are found specifically within the acrosomal vesicle of all mammalian spermatozoa. Acrosin is thought to be involved in the recognition and binding of the sperm to the zona pellucida of the ovum and the sperm penetration through the zona pellucida. Mouse knock-out mutants suggest that Acr- sperm have a selective disadvantage when they are in competition with Acr+ sper []. Short Name:  Pept_S1A_acrosin
Paste the following link

0 Child Features

1 Contains

DB identifier Type Name
IPR018114 Active_site Peptidase S1, trypsin family, active site

2 Cross Referencess

Identifier
PTHR24252
PIRSF001141

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0004252 IPR012267
GO:0001669 IPR012267

2 Ontology Annotations

GO Term Gene Name
GO:0004252 IPR012267
GO:0001669 IPR012267

1 Parent Features

DB identifier Type Name
IPR001314 Family Peptidase S1A, chymotrypsin-type

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9041140