| Type: | Domain | Name: | Invasin beta-domain of outer membrane |
| Description: | This domain is found in a group of beta-barrel porin-like outer membrane proteins from enteropathogenic Gram-negative bacteria. Intimins and invasins are virulence factors produced by pathogenic Gram-negative bacteria. They carry C-terminal extracellular passenger domains that are involved in adhesion to host cells and N-terminal beta domains that are embedded in the outer membrane. This entry represents the beta-barrel porin-like domain in the outer membrane [].Intimin is believed to mediate adherence and it is necessary for the production of attaching and effacing lesions on tissue culture cells []. Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells []. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins []. | Short Name: | Invasin_beta |
