Protein Domain : IPR001061

Type:  Family Name:  Transgelin-2
Description:  Transgelin belongs to the calponin family, whose members have an N-terminal calponin homology domain (CH) and the C-terminal calponin-like repeat. Transgelin (also known as SM22) is an actin binding protein localised to the cytoskeletal apparatus []. Transgelin is required in agonist-induced smooth muscle contraction and is involved in cell migration [, ]. It has tumour suppressive functions in certain cells [, ]. The function of transgelin-2, also known as SM22-beta, is not clear. It seem to have a unique developmentally regulated pattern of expression []. Short Name:  TAGLN2

0 Child Features

2 Contains

DB identifier Type Name
IPR001715 Domain Calponin homology domain
IPR000557 Repeat Calponin repeat

1 Cross References

Identifier
PTHR18959:SF44

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0051015 IPR001061

1 Ontology Annotations

GO Term Gene Name
GO:0051015 IPR001061

1 Parent Features

DB identifier Type Name
IPR003096 Family Smooth muscle protein/calponin

0 Proteins

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17082327
            9384215
            17464194
            12808045
            18378184
            12049783