Protein Domain : IPR001997

Type:  Family Name:  Calponin/LIMCH1
Description:  Calponin is a smooth muscle-specific, actin-, tropomyosin- and calmodulin-binding protein believed to be involved in regulation or modulation of contraction [, ]. Interaction of the protein with actin inhibits actomyosin MgATPase activity. Multiple isoforms are found in smooth muscle []. Calponin is a basic protein of ~34 kDa []. The protein contains three repeats of a well-conserved 26-residue domain (see ).This entry also includes LIM and calponin homology domains-containing protein 1 (LIMCH1), which contains a LIM zinc-binding domain and a CH (calponin-homology) domain. Short Name:  Calponin/LIMCH1

1 Child Features

DB identifier Type Name
IPR029980 Family LIM and calponin homology domains-containing protein 1

2 Contains

DB identifier Type Name
IPR001715 Domain Calponin homology domain
IPR000557 Repeat Calponin repeat

1 Cross References

Identifier
PR00889

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0003779 IPR001997
GO:0031032 IPR001997

2 Ontology Annotations

GO Term Gene Name
GO:0003779 IPR001997
GO:0031032 IPR001997

1 Parent Features

DB identifier Type Name
IPR003096 Family Smooth muscle protein/calponin

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8144658
            8370452
            8550594