3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0008200 | IPR012414 |
GO:0009405 | IPR012414 |
GO:0042151 | IPR012414 |
Type: | Family | Name: | BDS potassium channel toxin |
Description: | This entry represents the sea anemone type 3 (BDS) potassium channel toxins. Family members include toxin APETx1 and 2, and the antihypertensive and antiviral proteins BDS-I () and BDS-II () expressed by Anemonia sulcata. BDS-I is organised into a triple-stranded antiparallel beta-sheet, with an additional small antiparallel beta-sheet at the N terminus []. The proteins are known to specifically block the Kv3.4 potassium channel, and thus bring about a decrease in blood pressure []. Moreover, they inhibit the cytopathic effects of mouse hepatitis virus strain MHV-A59 on mouse liver cells, by an unknown mechanism []. | Short Name: | BDS_K_chnl_tox |
GO Term | Gene Name |
---|---|
GO:0008200 | IPR012414 |
GO:0009405 | IPR012414 |
GO:0042151 | IPR012414 |