Protein Domain : IPR012414

Type:  Family Name:  BDS potassium channel toxin
Description:  This entry represents the sea anemone type 3 (BDS) potassium channel toxins. Family members include toxin APETx1 and 2, and the antihypertensive and antiviral proteins BDS-I () and BDS-II () expressed by Anemonia sulcata. BDS-I is organised into a triple-stranded antiparallel beta-sheet, with an additional small antiparallel beta-sheet at the N terminus []. The proteins are known to specifically block the Kv3.4 potassium channel, and thus bring about a decrease in blood pressure []. Moreover, they inhibit the cytopathic effects of mouse hepatitis virus strain MHV-A59 on mouse liver cells, by an unknown mechanism []. Short Name:  BDS_K_chnl_tox

0 Child Features

0 Contains

1 Cross References

Identifier
PF07936

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0008200 IPR012414
GO:0009405 IPR012414
GO:0042151 IPR012414

3 Ontology Annotations

GO Term Gene Name
GO:0008200 IPR012414
GO:0009405 IPR012414
GO:0042151 IPR012414

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9506974
            2566326