Protein Domain : IPR017341

Type:  Family Name:  Membrane cofactor protein CD46
Description:  This entry represents a group of membrane cofactor proteins (also known as CD46 or TLX). Human CD46 acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue []. Rat CD46 may be involved in the fusion of the spermatozoa with the oocyte during fertilization []. Short Name:  CD46

0 Child Features

1 Contains

DB identifier Type Name
IPR000436 Domain Sushi/SCR/CCP domain

1 Cross References

Identifier
PIRSF037971

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0009986 IPR017341

1 Ontology Annotations

GO Term Gene Name
GO:0009986 IPR017341

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10843656
            15215199