3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0001848 | IPR011176 |
| GO:0045916 | IPR011176 |
| GO:0016021 | IPR011176 |
| Type: | Family | Name: | Complement control protein, vaccinia C3L |
| Description: | This group represents a complement control protein, vaccinia C3L type. The vaccinia virus complement control protein is involved in modulating the host inflammatory response by blocking both classical and alternative pathways of complement activity through its ability to bind host complement components C3b and C4b (complement 3b and 4b, respectively) []. By blocking complement activation at multiple sites, the complement control protein can down-regulate pro-inflammatory chemotactic factors (C3a, C4a, and C5a), resulting in reduced cellular influx and inflammation. | Short Name: | CIP_VAC_C3L |
| GO Term | Gene Name |
|---|---|
| GO:0001848 | IPR011176 |
| GO:0045916 | IPR011176 |
| GO:0016021 | IPR011176 |
