3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0003779 | IPR008379 |
| GO:0005198 | IPR008379 |
| GO:0005856 | IPR008379 |
| Type: | Domain | Name: | Band 4.1, C-terminal |
| Description: | There is a unique sequence domain at the C terminus of all known 4.1 proteins, known as the C-terminal domain (CTD). Mammalian CTDs are associated with a growing number of protein-protein interactions, although such activities have yet to be associated with invertebrate CTDs. Mammalian CTDs are generally defined by sequence alignment as encoded by exons 18-21. Comparison of known vertebrate 4.1 proteins with invertebrate 4.1 proteins indicates that mammalian 4.1 exon 19 represents a vertebrate adaptation that extends the sequence of the CTD with a Ser/Thr-rich sequence. The CTD was first described as a 22/24 kDa domain by chymotryptic digestion of erythrocyte 4.1 (4.1R). CTD is thought to represent an independent folding structure which has gained function since the divergence of vertebrates from invertebrates []. | Short Name: | Band_4.1_C |
| GO Term | Gene Name |
|---|---|
| GO:0003779 | IPR008379 |
| GO:0005198 | IPR008379 |
| GO:0005856 | IPR008379 |
