1 Contains
DB identifier | Type | Name |
---|---|---|
IPR013114 | Domain | Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ |
3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0008693 | IPR010083 |
GO:0006633 | IPR010083 |
GO:0005737 | IPR010083 |
Type: | Family | Name: | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA |
Description: | This enzyme, FabA, shows overlapping substrate specificity with FabZ with regard to chain length in fatty acid biosynthesis. It is commonly designated 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase as if it were specific for that chain length, but its specificity is broader; it is active even in the initiation of fatty acid biosynthesis. This enzyme can also isomerise trans-2-decenoyl-ACP to cis-3-decenoyl-ACP to bypass reduction by FabI and instead allow biosynthesis of unsaturated fatty acids. FabA cannot elongate unsaturated fatty acids. | Short Name: | FabA |
DB identifier | Type | Name |
---|---|---|
IPR013114 | Domain | Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ |
GO Term | Gene Name |
---|---|
GO:0008693 | IPR010083 |
GO:0006633 | IPR010083 |
GO:0005737 | IPR010083 |