Protein Domain : IPR029890

Type:  Family Name:  Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Description:  Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) possesses alkaline phosphodiesterase I and nucleotide pyrophosphatase activities []. ENPP1 hydrolyses extracellular nucleotide triphosphates to produce pyrophosphate and regulates bone mineralization, soft tissue calcification, and insulin signalling [, , ].Mutations in the ENPP1 gene cause several pathological calcification syndromes, such as idiopathic infantile arterial calcification (IIAC) [] and sssification of the posterior longitudinal ligament of the spine (OPLL) []. Short Name:  ENPP1
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10151:SF64

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004528 IPR029890
GO:0004551 IPR029890
GO:0005886 IPR029890

3 Ontology Annotations

GO Term Gene Name
GO:0004528 IPR029890
GO:0004551 IPR029890
GO:0005886 IPR029890

1 Parent Features

DB identifier Type Name
IPR024873 Family Ectonucleotide pyrophosphatase/phosphodiesterase family

0 Proteins

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            23027977
            12082181
            8001561
            17143316
            12881724
            10453738