| Type: | Domain | Name: | Methuselah, N-terminal domain |
| Description: | Drosophila Methuselah (Mth) mutants have a 35% increase in average lifespan and increased resistance to several forms of stress, including heat, starvation, and oxidative damage. The protein affected by this mutation is related to G protein-coupled receptors of the secretin receptor family. Mth, like secretin receptor family members, has a large N-terminal ectodomain, which may constitute the ligand binding site []. This entry represents the N-terminal domain of the Methuselah protein. | Short Name: | Methuselah_N_dom |
