| Type: | Family | Name: | Villin-2/3/4/5, plant |
| Description: | Villin belongs to the villin/gelsolin family, whose members are actin-modulating proteins that sever F-actin, cap the barbed ends of actin filaments preventing monomer exchange, and promote the nucleation step of actin polymerisation []. Villin is involved in actin remodelling necessary for many cellular processes requiring the actin cytoskeleton plasticity [, ].This entry represents villin-2/3/4/5 from plants, including AtVLN2/3/4/5 from Arabidopsis []. Arabidopsis contains at least five villin-like genes (AtVLNs) encoding five different VLN isoforms. AtVLN3 can sever actin filament []. AtVLN2 and AtVLN3 act redundantly in sclerenchyma development through bundling of actin filaments [, ]. AtVLN4 is involved in root hair growth through regulating actin organisation in a Ca2+-dependent manner []. AtVLN5 (UniProt: Q9LVC6) is an actin filament bundling and severing protein that is necessary for normal pollen tube growth []. | Short Name: | Villin-2/3/4/5_plant |
