Protein Domain : IPR029884

Type:  Family Name:  ORM1-like protein 1
Description:  ORM1-like protein 1 (ORML1) belongs to the ORMDL family, whose members may be involved in protein folding in the ER []. It is a negative regulator of sphingolipid synthesis []. ORMDL proteins mediate the feedback regulation of ceramide biosynthesis []. In mammalian cells, ceramide is a proapoptotic signaling sphingolipid. Short Name:  ORML1
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR12665:SF12

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0006672 IPR029884
GO:0090155 IPR029884
GO:0005789 IPR029884

3 Ontology Annotations

GO Term Gene Name
GO:0006672 IPR029884
GO:0090155 IPR029884
GO:0005789 IPR029884

1 Parent Features

DB identifier Type Name
IPR007203 Family ORMDL family

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12093374
            20182505
            23066021