Protein Domain : IPR017783

Type:  Family Name:  ABC transporter, choline, substrate-binding protein
Description:  Partial phylogenetic profiling [] suggests that the ABC transporter periplasmic binding proteins in this entry are involved in choline uptake for glycine betaine biosynthesis. Genomes often carry several paralogs, one encoded together with the permease and ATP-binding components, and another encoded next to a choline-sulphatase gene, suggesting that different members of this protein family interact with shared components and give some flexibility in substrate. Of the two proteins from Sinorhizobium meliloti 1021, one designated ChoX has been shown experimentally to bind choline (though not various related compounds such as betaine) and to be required for about 60 % of choline uptake []. In A. tumefaciens, the ABC-type choline transporter is encoded by the chromosomally located choXWV operon (ChoX, binding protein; ChoW, permease; and ChoV, ATPase). The ChoXWV transporter functions as a high-affinity choline transporter []. Short Name:  ABC_transptr_choline_sub-bd

0 Child Features

1 Contains

DB identifier Type Name
IPR007210 Domain ABC-type glycine betaine transport system, substrate-binding domain

1 Cross References

Identifier
TIGR03414

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0033265 IPR017783
GO:0015871 IPR017783
GO:0042597 IPR017783

3 Ontology Annotations

GO Term Gene Name
GO:0033265 IPR017783
GO:0015871 IPR017783
GO:0042597 IPR017783

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16930487
            15342567
            21803998