Protein Domain : IPR023532

Type:  Family Name:  H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type
Description:  Nop10 is a component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs). H/ACA snoRNPs are primarily responsible for catalysing the isomerisation of uridine to pseudouridine (Psi) in ribosomal and other cellular RNAs. The protein component of the H/ACA snoRNP consists of Cbf5, Gar1, Nhp2 and Nop10. The complex contains a stable core composed of Cbf5 and Nop10, to which Gar1 and Nhp2 subsequently bind. Nop10 has an essential role in the assembly and activity of these particles and binds directly to the Cbf5 to form the minimal active enzyme in archaea. The complex interacts with snoRNAs, Nop10 acting as a molecular adaptor for guiding snoRNP assembly []. Short Name:  Nop10_arc-typ
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0 Child Features

0 Contains

1 Cross References

Identifier
MF_00803

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0030515 IPR023532
GO:0001522 IPR023532
GO:0042254 IPR023532
GO:0072588 IPR023532

4 Ontology Annotations

GO Term Gene Name
GO:0030515 IPR023532
GO:0001522 IPR023532
GO:0042254 IPR023532
GO:0072588 IPR023532

1 Parent Features

DB identifier Type Name
IPR007264 Family H/ACA ribonucleoprotein complex, subunit Nop10

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            18473479