Protein Domain : IPR018312

Type:  Conserved_site Name:  Chromosomal replication control, initiator DnaA, conserved site
Description:  The bacterial dnaA protein [, , ] plays an important role in initiating and regulating chromosomal replication. DnaA is an ATP- and DNA-binding protein. It binds specifically to 9 bp nucleotide repeats known as dnaA boxes which are found in the chromosome origin of replication (oriC).DnaA is a protein of about 50 kDa that contains two conserved regions: the first is located in the N-terminal half and corresponds to the ATP-binding domain, the second is located in the C-terminal half and could be involved in DNA-binding. The protein may also bind the RNA polymerase beta subunit, the dnaB and dnaZ proteins, and the groE gene products (chaperonins) [].The signature pattern in this entry is located in the most conserved part of the putative DNA-binding domain. Short Name:  Chromosome_initiator_DnaA_CS
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0 Child Features

0 Contains

1 Cross References

Identifier
PS01008

4 Found Ins

DB identifier Type Name
IPR010921 Domain Trp repressor/replication initiator
IPR013159 Domain Chromosomal replication initiator, DnaA C-terminal
IPR020591 Family Chromosomal replication control, initiator DnaA-like
IPR001957 Family Chromosomal replication control, initiator DnaA

5 GO Annotations

GO Term Gene Name
GO:0003677 IPR018312
GO:0003688 IPR018312
GO:0005524 IPR018312
GO:0006270 IPR018312
GO:0006275 IPR018312

5 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR018312
GO:0003688 IPR018312
GO:0005524 IPR018312
GO:0006270 IPR018312
GO:0006275 IPR018312

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8110826
            2172087
            1779750
            2558436