Protein Domain : IPR020566

Type:  Family Name:  Histidine biosynthesis bifunctional protein HisB
Description:  This entry represents the histidine biosynthesis bifunctional protein HisB [, ], which contains an N-terminal histidinol phosphate phosphatase () and a C-terminal imidazoleglycerol-phosphate dehydratase () []. HisB catalyses steps 6 and 8 of L-histidine biosynthesis. The N-terminal histidinol phosphate phosphatase domain folds into a single domain that has similarity to the haloacid dehalogenase (HAD) enzyme family, with a zinc ion stabilising the conformation of an extended loop []. Short Name:  His_synth_bifunc_HisB
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0 Child Features

1 Contains

DB identifier Type Name
IPR020565 Conserved_site Imidazoleglycerol-phosphate dehydratase, conserved site

1 Cross References

Identifier
MF_01022

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004401 IPR020566
GO:0004424 IPR020566
GO:0000105 IPR020566

3 Ontology Annotations

GO Term Gene Name
GO:0004401 IPR020566
GO:0004424 IPR020566
GO:0000105 IPR020566

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16966333
            15042344
            13763426
            4349042