Protein Domain : IPR029592

Type:  Family Name:  Dual oxidase 2
Description:  This entry represents dual oxidase 2 (DUOX2). DUOX1 and DUOX2 are isoenzymes that belong to the family of NADPH oxidases (Nox) []. They function as calcium-dependent NADPH oxidases producing hydrogen peroxide (H2O2) which is required for thyroid hormone biosynthesis [] and the activity of lactoperoxidase (LPO) []. Duox2 is activated by activation of protein kinase C (PKC) and can be suppressed by thyroglobulin (Tg) [, ]. Short Name:  DUOX2
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR11972:SF53

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005509 IPR029592
GO:0016174 IPR029592
GO:0006590 IPR029592

3 Ontology Annotations

GO Term Gene Name
GO:0005509 IPR029592
GO:0016174 IPR029592
GO:0006590 IPR029592

1 Parent Features

DB identifier Type Name
IPR019791 Family Haem peroxidase, animal

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            19144650
            22874065
            22612456
            12824283