Protein Domain : IPR030160

Type:  Family Name:  Voltage-dependent calcium channel, T-type, alpha-1H subunit
Description:  This entry represents the T-type voltage-dependent calcium channel, alpha-1H subtype, also known as Cav3.2. Voltage-dependent calcium channels (VDCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. T-type VDCC belongs to low-voltage-activated (LVA) Ca2+ channels, whereas others belong to high-voltage-activated (HVA) Ca2+ channels.VDCCs consist of subunits. The alpha-1 subunit constitute the pore region which determines the fundamental channel properties []. Three types of alpha-1 subunit have been identified in T-type VDCCs molecules: alpha-1G [], alpha-1H [], and alpha-1I []. T-currents generated by the alpha-1I subunit display slow kinetics that differ markedly from the alpha-1G and alpha-1H currents [, , ]. Short Name:  VDCC_T_a1H

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10037:SF192

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0008332 IPR030160
GO:0070509 IPR030160
GO:0005891 IPR030160

3 Ontology Annotations

GO Term Gene Name
GO:0008332 IPR030160
GO:0070509 IPR030160
GO:0005891 IPR030160

1 Parent Features

DB identifier Type Name
IPR005445 Family Voltage-dependent calcium channel, T-type, alpha-1 subunit

0 Proteins

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9670923
            7516685
            10692398
            10749850
            10594642
            11073957