Type: | Domain | Name: | Sensory domain of two-component sensor kinase |
Description: | This entry represents the periplasmic sensor domain of sensor histidine kinases such as DcuS from E. coli []. This domain forms one of the components of the two-component signalling system that allows bacteria to adapt to changing environments. The ability of bacteria to monitor and adapt to their environment is crucial to their survival, and two-component signal transduction systems mediate most of these adaptive responses. One component is a histidine kinase sensor - this domain - most commonly part of a homodimeric transmembrane sensor protein, and the second component is a cytoplasmic response regulator. The two components interact in tandem through a phospho-transfer cascade []. | Short Name: | Sensory_dom |