Protein Domain : IPR030190

Type:  Family Name:  Macrolide export protein MacA
Description:  MacA is part of the MacAB-TolC complex (composed of an inner membrane transporter, MacB, a periplasmic membrane fusion protein, MacA, and an outer membrane component, TolC), which is a tripartite macrolide efflux transporter driven by hydrolysis of ATP []. MacA interacts with MacB and TolC []. MacA can bind rough-core lipopolysaccharide (R-LPS) specifically and with high affinity, suggesting that the complex could also transport R-LPS or a similar glycolipid []. Its protein structure has been solved []. Short Name:  MacA

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR30572:SF3

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0022891 IPR030190
GO:0006810 IPR030190
GO:0019898 IPR030190

3 Ontology Annotations

GO Term Gene Name
GO:0022891 IPR030190
GO:0006810 IPR030190
GO:0019898 IPR030190

1 Parent Features

DB identifier Type Name
IPR006143 Family RND efflux pump, membrane fusion protein

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            18955484
            19254725
            23974027
            21696464