Protein Domain : IPR030250

Type:  Family Name:  Multidrug resistance-associated protein 9
Description:  This entry represents the multidrug resistance-associated protein 9 (MRP9, also known as ABCC12) from animals. It belongs to the MRP (multidrug resistance protein) subfamily of the ATP-binding cassette (ABC) transporter family []. MRP9 may play a role during the latter part of the male meiotic prophase, spermatid development or in sperm function, as full-length MRP9 appears to be expressed only in testicular germ cells and sperm of mouse and boar [, ]. The ABC transporter family is a group of membrane proteins that use the hydrolysis of ATP to power the translocation of a wide variety of substrates across cellular membranes. ABC transporters minimally consist of two conserved regions: a highly conserved nucleotide-binding domain (NBD) and a less conserved transmembrane domain (TMD). Eukaryotic ABC proteins are usually organised either as full transporters (containing two NBDs and two TMDs), or as half transporters (containing one NBD and one TMD), that have to form homo- or heterodimers in order to constitute a functional protein []. Short Name:  MRP9

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR24223:SF10

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0005524 IPR030250
GO:0042626 IPR030250
GO:0055085 IPR030250
GO:0016021 IPR030250

4 Ontology Annotations

GO Term Gene Name
GO:0005524 IPR030250
GO:0042626 IPR030250
GO:0055085 IPR030250
GO:0016021 IPR030250

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11441126
            21103974
            21740521
            17472575