Protein Domain : IPR030279

Type:  Family Name:  ATP-dependent permease Mdl1/Mdl2
Description:  This entry represents the mitochondrial ATP-dependent permeases Mdl1/Mdl2 from fungi. They belongs to the ABC transporter family. They are half transporters, which have only one transmembrane domain and one nucleotide-binding domain []. In Saccharomyces cerevisiae, Mdl1 is localised in the inner membrane of mitochondria and is involved in peptide export [].The ABC transporter family is a group of membrane proteins that use the hydrolysis of ATP to power the translocation of a wide variety of substrates across cellular membranes. ABC transporters minimally consist of two conserved regions: a highly conserved nucleotide-binding domain (NBD) and a less conserved transmembrane domain (TMD). Eukaryotic ABC proteins are usually organised either as full transporters (containing two NBDs and two TMDs), or as half transporters (containing one NBD and one TMD), that have to form homo- or heterodimers in order to constitute a functional protein []. Short Name:  Mdl1/Mdl2

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR24221:SF124

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0005524 IPR030279
GO:0015421 IPR030279
GO:0090374 IPR030279
GO:0016021 IPR030279

4 Ontology Annotations

GO Term Gene Name
GO:0005524 IPR030279
GO:0015421 IPR030279
GO:0090374 IPR030279
GO:0016021 IPR030279

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11441126
            11251115
            15247210