Type: | Family | Name: | Na(+)/H(+) exchange regulatory cofactor NHERF |
Description: | This entry includes NHERF-1 and NHERF-2. They are PDZ domain-containing protein that functions as a scaffolding protein for the glutamate transporter GLAST. NHERF1 interacts with GLAST during ER export, while NHERF2 interacts with GLAST in the secretory pathway from the ER-Golgi intermediate compartment to the plasma membrane []. | Short Name: | NHERF-1/NHERF-2 |