| Type: | Domain | Name: | Beclin-1, BH3 domain |
| Description: | Beclin 1 is a tumour suppressor that coordinately regulates the autophagy and membrane trafficking involved in several physiological and pathological processes []. The BH3 domain of Beclin 1 is bound to, and inhibited by Bcl-2 or Bcl-XL []. This interaction enables Bcl-2 to function not only as an antiapoptotic protein, but also as an antiautophagy protein []. | Short Name: | BH3_dom |
