| Type: | Active_site | Name: | Delta-aminolevulinic acid dehydratase, active site |
| Description: | Delta-aminolevulinic acid dehydratase () (ALAD) or porphobilinogen synthase [] catalyses the second step in the biosynthesis of heme, the condensation of two molecules of5-aminolevulinate to form porphobilinogen. The enzyme is an oligomer composed of eight identical subunits. Each of the subunits binds an atom of zinc or ofmagnesium (in plants). A lysine has been implicated in the catalytic mechanism []. The sequence of the region in the vicinity of the active site residue is conserved in ALAD from various prokaryotic and eukaryotic species. | Short Name: | ALAD_AS |
