3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0009405 | IPR003059 |
| GO:0019835 | IPR003059 |
| GO:0019867 | IPR003059 |
| Type: | Family | Name: | Colicin lysis protein |
| Description: | The DNA sequence of the entire colicin E2 operon has been determined [].The operon comprises the colicin activity gene (ceaB), the colicin immunity gene (ceiB) and the lysis gene (celB), which is essential for colicinrelease from producing cells []. A putative LexA binding site is locatedupstream from ceaB, and a rho-independent terminator structure is located downstream from celB []. Comparison of the amino acid sequences of colicinE2 and cloacin DF13 reveal extensive similarity. These colicins have different modes of action and recognise different cell surface receptors;the two major regions of heterology at the C terminus, and in the C-terminal end of the central region are thought to correspond to the catalytic and receptor-recognition domains, respectively []. Sequence similarities between colicins E2, A and E1 [] are less striking.The colicin E2 (pyocin) immunity protein does not share similarity with either the colicin E3 or cloacin DF13 [] immunity proteins. By contrast,the lysis proteins of the ColE2, ColE1 and CloDF13 plasmids are almost identical except in the N-terminal regions, which themselves are similar tolipoprotein signal peptides []. Processing of the ColE2 prolysis proteinto the mature form is prevented by globomycin, a specific inhibitor of the lipoprotein signal peptidase []. The mature ColE2 lysis protein is locatedin the cell envelope []. | Short Name: | Lysis_col |
| GO Term | Gene Name |
|---|---|
| GO:0009405 | IPR003059 |
| GO:0019835 | IPR003059 |
| GO:0019867 | IPR003059 |
