Type: | Domain | Name: | NADPH oxidase subunit p47Phox, C-terminal |
Description: | The C-terminal domain of the phagocyte NADPH oxidase subunit p47Phox contains conserved PxxP motifs that allow binding to SH3 domains, with subsequent activation of the NADPH oxidase, and generation of superoxide, which plays a crucial role in host defence against microbial infection []. | Short Name: | NADPH_oxidase_p47Phox_C |