Type: | Domain | Name: | Domain of unknown function DUF1899 |
Description: | Coronins are evoluntionarily conserved proteins, mainly involved in actin cytoskeleton organisation. Typically Coronins contain a DUF1899 domain, a series of WD40 repeats, a DUF1900 domain () and a C-terminal coiled-coil domain []. This entry represents the N-terminal DUF1899 domain. A putative actin binding site just downstream of a phosphoserine modification site is proposed to be located in this domain [, , ].Proteins with this domain include most of the Coronin homologues (besides Coronin 7 []) and Villidin from Dictyostelium discoideum. | Short Name: | DUF1899 |