Protein Domain : IPR030462

Type:  Family Name:  Beta-catenin/armadillo-related protein 1
Description:  This entry represents beta-catenin/armadillo-related protein 1, also know as BAR-1, from nematoda. C. elegans expresses three beta-catenin-related proteins, BAR-1, HMP-2, and WRM-1 []. They are armadillo repeat proteins found in adherens junctions, where they interact with the cytoplasmic domain of classical cadherins and with alpha-catenin []. BAR-1 functions in Wnt signal transduction []. Loss-of-function of BAR-1 slows development and activates the Wnt pathway []. WRM-1 and HMP-2 can substitute for BAR-1 in C. elegans when expressed from the bar-1 promoter []. Short Name:  BAR-1

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR23315:SF55

0 Found In

8 GO Annotations

GO Term Gene Name
GO:0003713 IPR030462
GO:0008134 IPR030462
GO:0007155 IPR030462
GO:0016055 IPR030462
GO:0048513 IPR030462
GO:0005634 IPR030462
GO:0005737 IPR030462
GO:0005913 IPR030462

8 Ontology Annotations

GO Term Gene Name
GO:0003713 IPR030462
GO:0008134 IPR030462
GO:0007155 IPR030462
GO:0016055 IPR030462
GO:0048513 IPR030462
GO:0005634 IPR030462
GO:0005737 IPR030462
GO:0005913 IPR030462

1 Parent Features

DB identifier Type Name
IPR013284 Family Beta-catenin

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            19759396
            11560894
            9834184
            24819947