| Type: | Family | Name: | Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha |
| Description: | This entry includes pyruvate dehydrogenase E1 component subunit alpha (PdhA) from Bacillus subtilis and 3-methyl-2-oxobutanoate dehydrogenase subunit alpha (BkdA) from Mycobacterium tuberculosis. The pyruvate dehydrogenase complex catalyses the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). BkdA is a component of the branched-chain alpha-ketoacid dehydrogenase (BCKADH) complex that catalyses the overall conversion of branched-chain alpha-ketoacids to acyl-CoA and CO2 []. | Short Name: | PdhA/BkdA |
