Type: | Family | Name: | Radical SAM family RiPP maturation amino acid epimerase |
Description: | This entry represents PoyD and its homologues. These are divergent putative radical SAM enzymes, with the classical CxxxCxxC motif but not found in . PoyD appears responsible for catalysing a unidirectional L-to-D epimerization of 18 the 48 residues in the core peptide of the first characterised polytheonamide. The RiPP (ribosomally translated natural product) precursor, and peptides encoded near many other members of this family, belong to the nitrile hydratase leader peptide (NHLP) family []. | Short Name: | rSAM_PoyD |