Protein Domain : IPR018294

Type:  Conserved_site Name:  4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site
Description:  4-diphosphocytidyl-2C-methyl-D-erythritol synthase, a bacterial ispD protein, catalyzes the third step of the deoxyxylulose-5-phosphate pathway (DXP) of isoprenoid biosynthesis; the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate []. The isoprenoid pathway is a well known target for anti-infective drug development [, ].This entry represents a pattern that identifies IspD. The pattern is centred on a central conserved region that contains a conserved Asp and Arg residues. Short Name:  ISPD_synthase_CS

0 Child Features

0 Contains

1 Cross References

Identifier
PS01295

1 Found In

DB identifier Type Name
IPR001228 Family 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

2 GO Annotations

GO Term Gene Name
GO:0003824 IPR018294
GO:0008299 IPR018294

2 Ontology Annotations

GO Term Gene Name
GO:0003824 IPR018294
GO:0008299 IPR018294

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10841550
            17081012
            17921290