Protein Domain : IPR003755

Type:  Family Name:  HPr(Ser) kinase/phosphorylase
Description:  This entry represents the bifunctional HPr serine kinase/phosphorylase (HprK/P). It catalyses the phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). It also catalyses thedephosphorylation of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. HprK/P is the sensor in a multicomponent phosphorelay system that controls catabolite repression, sugar transport and carbon metabolism in Gram-positive bacteria [, ]. Short Name:  HPr(Ser)_kin/Pase
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0 Child Features

2 Contains

DB identifier Type Name
IPR011126 Domain HPr(Ser) kinase/phosphorylase, N-terminal
IPR011104 Domain HPr kinase/phosphorylase, C-terminal

2 Cross Referencess

Identifier
TIGR00679
MF_01249

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0000155 IPR003755
GO:0005524 IPR003755
GO:0000160 IPR003755
GO:0006109 IPR003755

4 Ontology Annotations

GO Term Gene Name
GO:0000155 IPR003755
GO:0005524 IPR003755
GO:0000160 IPR003755
GO:0006109 IPR003755

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9987110
            15023355