Protein Domain : IPR023689

Type:  Family Name:  2,3-diketo-L-gulonate reductase
Description:  This entry represents a family of bacterial 2,3-diketo-L-gulonate reductases, which catalyse the reduction of 2,3-diketo-L-gulonate in the presence of NADH []. The gene operon yiaK-S (of which yiaK encodes for the 2,3-diketo-L-gulonate reductase) is believed to encode proteins which are involved in the utilisation of rare sugars for growth. This enzyme relies on NAD-tartrate binding to produce a more open active site; the conformation of the free enzyme is incompatible with substrate binding []. Short Name:  Diketo_gul_Rdtase
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0 Child Features

0 Contains

1 Cross References

Identifier
MF_00820

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0016616 IPR023689
GO:0047559 IPR023689
GO:0070403 IPR023689
GO:0055114 IPR023689

4 Ontology Annotations

GO Term Gene Name
GO:0016616 IPR023689
GO:0047559 IPR023689
GO:0070403 IPR023689
GO:0055114 IPR023689

1 Parent Features

DB identifier Type Name
IPR003767 Family Malate/L-lactate dehydrogenase

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11741871
            14718529