3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0006935 | IPR031133 |
GO:0042384 | IPR031133 |
GO:0035869 | IPR031133 |
Type: | Family | Name: | Protein fantom, invertebrates |
Description: | Protein fantom (NPHP8/RPGRIP1L) is a ciliary gene that, when mutated, causes nephronophthisis (NPHP), the most frequent genetic cause of end-stage renal failure in children and young adults. In worms, cilia are only present at the tips of the sensory neurons in the head and tail to sense environmental signals. The Caenorhabditis elegans homologue of NPHP8 plays an important role in cilia formation and cilia-mediated chemosensation []. | Short Name: | NPHP8_invert |
GO Term | Gene Name |
---|---|
GO:0006935 | IPR031133 |
GO:0042384 | IPR031133 |
GO:0035869 | IPR031133 |